PREMIX ANTIBIOTIC

Clortetradem 10%

premix for medicated feed, 100 mg/g chlortetracycline HCl, for pigs and poultry (chickens, turkeys).

Formula

1 gram of product contains:

Active substance
Chlortetracycline hydrochloride 100 mg

Target species

Pigs, poultry (chickens and hens)

Indications

In pigs: CLORTETRADEM 10% premix is indicated for treatment and control of respiratory and systemic infections associated with organisms chlortetracycline-susceptible: Haemophillus parasuis, Corynebacterium, Erysipelothrix rhusiopatiae, Streptococcus hyicus, Actinobacillus pleuropneumoniae, Pasteurella multocida,  Mycoplasma spp. etc.

In poultry (chickens, turkeys): CLORTETRADEM 10% premix is indicated for treatment and control of respiratory and systemic infections associated with organisms sensitive to chlortetracycline-susceptible: Streptococcus spp., Bordetella bronchiseptica, Haemophillus paragallinarum, Pasteurella multocida, Fusobacterium, Mycoplasma, Chlamydia, etc.

Administration

CLORTETRADEM 10% premix is administered via drinking water in the following dosages:

Pigs: 110 mg CLORTETRADEM 10% premix /kg b.w./day administered for 5 consecutive days.

Poultry (chickens, turkeys): 110 mg CLORTETRADEM 10% premix /kg b.w./day, administered for 5 consecutive days.


The uptake of medicated feed is dependant on the clinical condition of animals. In order to obtain the correct dosage, the concentration in feed may have to be adjusted.

The use of suitable calibrating weighing equipment is recommended if part packs are used.

For any information regarding this veterinary medicinal product, please contact the local representative of the marketing authorization holder.

Contraindications

Do not use in animals with known hypersensitivity to tetracyclines.

Side effects

In some cases, the animal with severe renal failure could develop adverse reactions characterized by: anorexia, vomit, diarrhea, abdominal colic, painful defecation.

The possible toxic phenomena are due to chlortetracycline high concentrations in blood and tissues, which occur after the administration of multiple high doses and in low intervals or in case of severe renal failure.

Digestive apparatus: anorexia, vomits, diarrhea, abdominal colic and pancreatitis; administered for long periods of time can produce staphylococcal enteritis or candidosis (oral, intestinal, pulmonary).

Teeth: dental pigmentation, caries and dental enamel hypoplasia in suckling and young off-springs to who mothers were treated with CLORTETRADEM 10% premix in the latest period of gestation or after birth.

Special precautions for storage

Keep away from reach and sight of children!

Store in original packaging at temperatures below 25oC, protected from moisture and direct sunlight.

Shelf life of the veterinary medicinal product as packaged for sale: 2 years.
Shelf life after dilution in drinking water, according to directions: 24 hours.

Shelf life after first opening of the package: 7 days.

Shelf life after incorporation into meal: 7 days

Do not use after expiry date which is stated on the label.

Advice on correct administration

During treatment, the animals should eat only medicated feed. To ensure a correct dosage, body weight should be determined as accurately as possible to avoid underdosing.

Withdrawal period

Pigs, poultry (chickens, turkeys):

Edible tissues: 28 days after cessation of oral medication.

For eggs: 7 days after cessation of oral medication

Special warnings

People with known hypersensitivity to any of the product ingredients should avoid contact with the veterinary medicinal product. To prevent any unpleasant effects, personal protective equipment consisting in rubber gloves, goggles and dust masks should be worn when administering the product. Wash hands and exposed skin after use.

In case of accidental ingestion or the occurrence of symptoms characterized by skin rash, seek medical advice. Serious symptoms such as face swelling, lips or eye lids, accompanied by breath difficulties, need immediate medical attention.

Due to variability (time, geographical) in susceptibility of bacteria for chlortetracycline, bacteriological sampling and susceptibility testing of microorganisms from diseased birds on farm are highly recommended. A high resistance rate of E.coli, isolated from chickens, against tetracyclines has been documented. Therefore the product should be used for the treatment of infections caused by E.coli only after susceptibility testing has been carried out. As eradication of the target pathogens may not be achieved, medication should therefore be combined with good management practices, e.g. good hygiene, proper ventilation, no overstocking.

Special precautions for the disposal of unused product or waste materials

For the environmental protection, medicines should not be disposed of via wastewater or household waste. Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal prod- ucts should be disposed of in accordance with local requirements.

Other information

Pack sizes: 10g, 25g, 50g, 100g, 500g, 1000g, 5kg, 10kg, 25kg, 50 kg.
Not all pack sizes may be marketed.